elegans research are introduced and discussed. Most importantly, links and literature that will allow a researcher to learn about different topics in C. We provide a general background to working with worms, including a selective list of some of the more significant research results so far and of the many current research topics being studied in worms we also include some general laboratory recipes and handling tips from our own experiences with beginning research students. Just as significantly, the community of researchers working with worms is highly interactive and collaborative, which makes it attractive to newcomers to the field, including undergraduate researchers. It was also the first genome from a multicellular organism to be sequenced. elegans an appealing and effective model organism are that it is easy to work with in the lab, with minimal nutritional and growth requirements, that it produces a large number of offspring by self-fertilization within a few days, and that it has been thoroughly studied. The nematode worm Caenorhabditis elegans has become one of the most widely used model organisms for nearly every aspect of biology. It is also appropriate for introducing undergraduate students to research, and some of its strengths and challenges for this purpose are discussed. elegans because of its versatility as a research organism. In fact, many novel techniques and ideas are initially tested in C. elegans was the first multicellular organism to have its genome sequenced, so many of the standard genomic methods have also been pioneered in C. elegans, and three different recent Nobel Prizes have recognized six researchers working with worms. Many different aspects of biology are being studied in C. elegans begin with the generation and analysis of mutants that affect a specific biological process, so genetic techniques are the foundation of worm research. Since its introduction as a laboratory organism 50 years ago, the nematode worm Caenorhabditis elegans has become one of the most widely used and versatile models for nearly all aspects of biological and genomic research.
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